Evidence supporting the use of: Devil's Club
For the body system: Glandular System

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Devil's Club (Oplopanax horridus) has a long history of use among Indigenous peoples of the Pacific Northwest of North America. Traditionally, it has been valued as a medicinal plant for a variety of ailments, including those believed to be related to the glandular or endocrine system. Folk uses include employing Devil's Club as a remedy for diabetes (suggesting support for pancreatic function), as well as for tuberculosis, arthritis, and as a general "blood purifier." Preparations were often made by decocting the roots or inner bark.

In terms of scientific validation, research is limited. Some modern herbalists suggest that Devil's Club may have adaptogenic properties, potentially supporting the body’s response to stress, which could indirectly influence the endocrine system. However, robust clinical trials or laboratory studies demonstrating direct benefit to the glandular system are lacking. A small number of in vitro and animal studies have hinted at hypoglycemic activity, but this evidence is preliminary and insufficient to establish efficacy or safety for endocrine or glandular support in humans.

In summary, the use of Devil's Club to support the glandular system is justified primarily by traditional knowledge rather than by modern scientific evidence. Its traditional use for diabetes and as a general tonic underpins its historical association with glandular health, but current scientific evidence is insufficient to substantiate these claims.

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Products containing Devil's Club

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