Evidence supporting the use of: Ginsenosides
For the body system: Glandular System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Ginsenosides are the primary active compounds found in ginseng (Panax ginseng and Panax quinquefolius) and have been the focus of numerous scientific studies for their potential effects on the glandular (endocrine) system. Research indicates that ginsenosides can modulate hormone production and secretion, particularly influencing the hypothalamic-pituitary-adrenal (HPA) axis, which plays a crucial role in stress response and overall endocrine function. Several animal and in vitro studies have demonstrated that ginsenosides may impact the secretion of hormones such as cortisol, ACTH, and insulin, suggesting a regulatory effect on adrenal and pancreatic glands. Some human studies have shown that ginseng supplementation can help modulate blood sugar levels and may improve symptoms of adrenal fatigue or stress, though the data are mixed and often limited by small sample sizes and inconsistent methodologies.

Despite these promising findings, the evidence is not robust or consistent enough to unequivocally support the use of ginsenosides for glandular system support in humans. Most clinical trials are of modest quality, and more research is needed to clarify the therapeutic role, optimal dosing, and long-term safety. Traditional Chinese Medicine has long used ginseng for vitality and stress, which overlaps with glandular function, but in terms of scientific validation, the current evidence warrants a moderate rating.

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Products containing Ginsenosides

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