Evidence supporting the use of: Isothiocyanates
For the body system: Glandular System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Isothiocyanates are compounds found in cruciferous vegetables such as broccoli, Brussels sprouts, and cabbage. They have been widely studied for their biological effects, particularly in relation to cancer prevention and detoxification processes. The glandular system, which includes hormone-producing glands such as the thyroid, adrenal, and pituitary glands, can be influenced by isothiocyanates primarily due to their impact on hormone metabolism and detoxification enzymes. Scientific studies suggest that isothiocyanates, especially sulforaphane and indole-3-carbinol, can modulate enzymatic pathways involved in the metabolism of estrogens and other hormones, potentially reducing the risk of hormone-dependent cancers (e.g., breast and prostate cancer). They are also known to induce phase II detoxification enzymes, which help the body process and eliminate toxins, indirectly supporting glandular health. Some in vitro and animal studies show that isothiocyanates can influence thyroid function, though excessive intake may suppress thyroid hormone synthesis due to inhibition of iodine uptake. Overall, while there is substantial scientific evidence pointing to the broad health benefits of isothiocyanates and their impact on hormone metabolism and detoxification, direct evidence for their use in broadly “supporting the glandular system” in humans is moderate and somewhat indirect. More clinical research is needed to establish specific benefits for each gland. Thus, a moderate rating is warranted based on current evidence.

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Products containing Isothiocyanates

We currently have no products on Vitabase that contain this ingredient.