Evidence supporting the use of: Macamides
For the body system: Glandular System

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Macamides are unique bioactive compounds found in maca (Lepidium meyenii), a root traditionally consumed in the Andes for its purported health benefits. Historically, maca has been used in Peruvian traditional medicine to support vitality, stamina, reproductive health, and hormonal balance. The glandular system—encompassing endocrine glands like the pituitary, thyroid, and adrenal glands—has been a focus of these traditional uses, particularly relating to energy, fertility, and stress response.

Scientific studies on macamides themselves are limited, with most research focusing on whole maca extracts. Some animal and in vitro studies suggest maca may influence hormonal activity and support the adrenal and reproductive glands, but direct evidence for macamides’ effects on the glandular system is sparse. A few studies have shown that macamides might contribute to the adaptogenic properties of maca, potentially helping the body manage physical and mental stress, which is related to glandular function. However, robust human clinical trials isolating macamides are lacking.

In summary, the use of macamides (via maca root) to support the glandular system is primarily justified by traditional use, with limited, low-quality scientific evidence suggesting possible benefits. Most claims are extrapolated from historical usage and the broader effects seen in maca root studies, rather than direct evidence for macamides themselves.

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Products containing macamides

We currently have no products on Vitabase that contain this ingredient.