Evidence supporting the use of: Sulforaphane
For the body system: Glandular System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Sulforaphane is a naturally occurring isothiocyanate found in cruciferous vegetables like broccoli, Brussels sprouts, and cabbage. Its use to support the glandular system, particularly the endocrine glands such as the thyroid, pancreas, and adrenal glands, has scientific grounding, though the evidence is still emerging and not definitive. Sulforaphane has been shown in numerous in vitro and animal studies to activate the Nrf2 pathway, which boosts the body’s antioxidant defenses and protects cells from oxidative stress. This cellular protection is relevant to the glandular system because endocrine glands are sensitive to oxidative damage, which can impair hormone production and secretion.

Additionally, sulforaphane has demonstrated the ability to modulate inflammatory processes and may help maintain cellular health in glands by reducing chronic inflammation. There is some evidence that sulforaphane can influence detoxification enzymes, which may indirectly support the function of endocrine glands by reducing the burden of environmental toxins. While there are a few small human studies suggesting beneficial effects on markers of oxidative stress and inflammation, direct clinical evidence for sulforaphane supporting the overall glandular (endocrine) system in humans is limited. Most research focuses on its role in cancer prevention, neuroprotection, and metabolic health rather than direct glandular support. Therefore, the evidence for sulforaphane’s use in supporting the glandular system is scientific, but moderate, and ongoing research is needed to clarify its specific benefits.

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Products containing Sulforaphane

We currently have no products on Vitabase that contain this ingredient.