Evidence supporting the use of: Triterpene Saponin
For the body system: Glandular System
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Triterpene saponins are a class of chemical compounds widely found in plants such as licorice (Glycyrrhiza glabra), ginseng (Panax ginseng), and others. Their use to support the glandular system—meaning the body’s network of hormone-producing glands—is primarily rooted in traditional medicine practices. In Traditional Chinese Medicine (TCM) and Ayurveda, herbs rich in triterpene saponins have been recommended for centuries to promote vitality, support adrenal function, and balance hormones. For example, ginseng has been used to “tonify Qi” and support the endocrine system, while licorice has been used to harmonize other herbs and support adrenal glands. However, direct scientific evidence linking triterpene saponins specifically to support of the overall glandular system is limited. Some laboratory and animal studies suggest that certain triterpene saponins can modulate stress response and may have mild effects on hormone metabolism, but these findings are not robust or directly translatable to comprehensive glandular system support in humans. Most clinical studies focus on single organs (e.g., adrenal or thyroid) or on immune modulation rather than broad glandular system effects. Therefore, while traditional use is well-documented, modern scientific validation is limited, warranting a moderate evidence rating.
Other ingredients that support Glandular System
7-Keto-DHEAadrenal cortex
alfalfa
amino acids
ashwagandha
astragalus
waterhyssop
basil
black cohosh
sesame
bovine
bovine kidney
bovine liver
bovine pancreas
broccoli
brussel sprouts
bupleurum falcatum
bасора
caterpillar mushroom
chaga mushroom
chaste tree
cinnamon
coenzyme Q10 (CoQ10)
colostrum
Coptis chinensis
cordyceps
cowage seed
turmeric
turmeric
dandelion
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
eleuthero
fennel
forskohlii root
fruit and vegetable blend (proprietary)
gamma linolenic acid (GLA)
garlic bulb
ginseng
gokhru
gooseberry
greek mountain tea
onion
green tea
greens blend (proprietary)
guayusa
guggul
iodine
iron
jujube
kale
kelp
l-tryptophan
l-tyrosine
lavender
licorice root
linoleic acid (LA)
liquid liver fractions
lophatherum leaf
maca
magnesium
maitake mushroom
manganese
melatonin
milk thistle
moringa
motherwort
nettle
niacin (vitamin B3)
oleanolic acid
omega-6 fatty acids
pantothenic acid (vitamin B5)
parsley
phytocannabinoids
pregnenolone
protein
pumpkin
pyridoxal-5-phosphate (P-5-P)
rehmannia glutinosa
reishi mushroom
rhodiola
riboflavin (vitamin B2)
rose oil
sage
saw palmetto
scrophularia root
selenium
soybean
tongkat ali
tribulus
vegetable blend (proprietary)
velvet bean
vitamin A
vitamin B
vitamin B6
vitamin C
vitamin D
vitamin D3
vitamin E
seaweed
water
watercress
wheat grass
whole adrenal glandular
wild yam
zinc
β-nicotinamide mononucleotide (NMN)
red clover
suma
jiaogulan
gastrodia
capsicum
hedychium spicatum
tinospora cordifolia
bee pollen
lingzhi
dioscorea
eucommia
ganoderma
lotus seed
oriental arborvitae
royal jelly
polyphenols
trace minerals
anemarrhena asphodeloides
noni
hypothalamus
herbal blend (proprietary)
algae
thyroid substance
ashitaba
bladderwrack
7,8-Dihydroxyflavone
Aralia
Antler
Anamarrhena
Ajuga
Ascophyllum nodosum
Asteracea
Acemannan
Agnuside
Ashoka
Anemarrhena
Animal protein
Blue Cohosh
Black Seed
Babchi
Bidens pilosa
Brown Algae
Brassica
Beef
Beef liver
Barleria
Berberis (unspecified)
Bovine Protein
Bulbine natalensis
Brazil nut
Banyan
Barbasco
Bee products
Babassu
Bupleurum
Camellia sinensis
Cinnamomum
Clary sage
Chinese Mountain Ant
Cucurbita
Cod Liver Oil
Codonopsis
Cruciferous
Cyanotis Vaga
Chinese Thoroughwax
Ceanothus integerrimus
Celastrus
Canscora
Didymocarpus
DHEA
Dendrobium
diiodotyrosine
Deer Velvet
Dong Quai
Diosgenin
Devil's Club
Dwarf Morning Glory
Eurycomanone
Elk antler
Eurycoma Longifolia
Essential Oil Blend
Eucommia ulmoides
Fenuside
Fatty acids
False Unicorn Root
Fadogia agrestis
Himalayan Salt
jasmine
Molasses
Sandalwood
Vervain