Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Vitexicarpin, also known as casticin, is a flavonoid compound found primarily in the fruit of Vitex agnus-castus (chaste tree). Its use in supporting the glandular system—especially female reproductive hormones—derives from traditional herbal medicine. Historically, Vitex agnus-castus has been used for centuries in Europe and the Mediterranean to address menstrual disorders, premenstrual syndrome (PMS), and symptoms related to menopause, all of which are tied to glandular (endocrine) function. The herb was believed to influence the pituitary gland, thereby impacting the balance of hormones such as prolactin and progesterone.

Modern research on casticin specifically is limited, with most studies focusing on the whole fruit extract rather than the isolated compound. Some preclinical studies suggest casticin may have modulatory effects on estrogen and prolactin levels, but robust clinical data in humans are lacking. The European Medicines Agency and other authoritative bodies recognize the traditional use of Vitex agnus-castus for menstrual irregularities, but they also note that more high-quality research is needed to confirm efficacy and clarify mechanisms.

In summary, the use of Vitexicarpin for glandular system support is justified primarily by traditional use, with limited but suggestive scientific rationale. The overall evidence is moderate as per tradition (rating 2/5), but weak in terms of direct scientific proof for Vitexicarpin itself.

More about Vitexicarpin
More about Glandular System

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Other body systems supported by Vitexicarpin

Female Reproductive System
Glandular System
Ovaries
Progesterone
Reproductive System
Uterus

Products containing Vitexicarpin

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