Evidence supporting the use of: Anthocyanins
For the health condition: Glaucoma

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Anthocyanins are naturally occurring flavonoid compounds found in various fruits and vegetables, especially those with red, blue, or purple pigmentation (such as blueberries, blackcurrants, and bilberries). Their use for supporting or treating glaucoma is based primarily on scientific research rather than traditional medical systems. The proposed mechanism is that anthocyanins possess potent antioxidant and anti-inflammatory properties, which may help protect retinal ganglion cells and support microvascular health in the eye. Some animal studies and small human trials have suggested that anthocyanin supplementation can reduce intraocular pressure (IOP), a major risk factor in glaucoma, and improve visual function or blood flow to the optic nerve.

However, the evidence is currently limited. Most clinical studies are small, short-term, and sometimes use mixed preparations rather than isolated anthocyanins. For example, small clinical trials with bilberry extract (rich in anthocyanins) have reported modest reductions in IOP among glaucoma patients, but these findings are not yet robust or widely replicated. There is a need for larger, well-designed randomized controlled trials to confirm the efficacy and safety of anthocyanins for glaucoma specifically. At present, anthocyanins may be considered as an adjunct for general eye health, but should not replace conventional glaucoma therapies. Their use is justified by early scientific evidence, but the strength and quality of this evidence are currently modest.

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