Evidence supporting the use of: Ginkgo Flavonglycosides
For the health condition: Glaucoma

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ginkgo flavonglycosides, the active compounds extracted from Ginkgo biloba leaves, have been investigated for their potential neuroprotective effects in glaucoma. Glaucoma is characterized by progressive optic nerve damage, often associated with elevated intraocular pressure (IOP) and impaired ocular blood flow. Several small clinical studies and experimental models suggest that Ginkgo biloba extract may improve ocular blood flow and exert antioxidative and anti-apoptotic effects, which could theoretically benefit glaucoma patients. For example, a randomized, placebo-controlled crossover trial (Quaranta et al., 2003) showed that Ginkgo biloba extract (GBE) improved pre-existing visual field damage in some patients with normal tension glaucoma. Other studies have demonstrated increased ocular blood flow with GBE supplementation. However, most trials are small, short-term, and sometimes methodologically limited. Major ophthalmology guidelines do not endorse Ginkgo as a standard therapy for glaucoma, and its effect on intraocular pressure is minimal or absent. Therefore, while there is some preliminary scientific evidence supporting the use of Ginkgo flavonglycosides for glaucoma, it is weak and not conclusive. Ginkgo is not a replacement for established glaucoma treatments, and patients should consult their ophthalmologist before using it as an adjunct therapy.

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