Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Caesalpinia crista, also known as “Fever Nut” or “Karanja,” is sometimes cited in traditional Ayurvedic and folk medicine texts for its diverse medicinal properties, including use for thyroid disorders such as goiter. Historical references in Ayurvedic literature suggest that the seeds and other parts of the plant were used for “glandular swellings” and to balance the body’s metabolism, which practitioners interpreted as being relevant to thyroid health. However, these uses are based largely on tradition, empirical observation, and energetic principles rather than modern scientific understanding of thyroid physiology or iodine metabolism.

There is little to no direct scientific evidence to support the efficacy of Caesalpinia crista specifically for goiter, which is most often caused by iodine deficiency or autoimmune thyroiditis. Some preclinical studies indicate that Caesalpinia crista contains bioactive compounds such as flavonoids and alkaloids, and it exhibits antioxidant and anti-inflammatory properties. While these general effects could theoretically be beneficial for certain aspects of thyroid health, no well-designed clinical trials or laboratory studies have specifically demonstrated its effectiveness for treating or shrinking goiter.

In summary, the use of Caesalpinia crista for goiter is primarily rooted in traditional use rather than validated by scientific research, and the evidence is weak (rated 1), consisting mainly of anecdotal and historical references rather than clinical studies.

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