Relationship: Goiter and iodine

Evidence supporting the use of: Iodine
For the health condition: Goiter

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Source of validity: Scientific
Rating (out of 5): 5

Iodine is scientifically validated as an effective treatment and preventive measure for goiter, particularly in cases caused by iodine deficiency. Goiter refers to the abnormal enlargement of the thyroid gland, and one of the most common causes globally is insufficient iodine intake. The thyroid gland requires iodine to synthesize thyroid hormones (thyroxine [T4] and triiodothyronine [T3]), which are essential for regulating metabolism. When dietary iodine is lacking, the thyroid cannot produce enough hormones, leading to increased stimulation by thyroid-stimulating hormone (TSH) and subsequent gland enlargement (goiter).

Historical intervention studies and public health initiatives have demonstrated that iodine supplementation, such as iodized salt, dramatically reduces the incidence of goiter in previously endemic regions. The introduction of universal salt iodization has been credited with virtually eradicating endemic goiter in many countries. Clinical trials and epidemiological data strongly support the role of iodine in thyroid health, specifically for the prevention and treatment of simple (non-toxic) goiter due to iodine deficiency.

However, it is important to distinguish between goiters caused by iodine deficiency and those due to other factors (e.g., autoimmune disease, thyroid nodules, or excess iodine), as iodine supplementation is not appropriate in all cases. In summary, the use of iodine for goiter associated with deficiency is one of the most well-established examples of nutritional intervention in medicine, supported by robust scientific evidence and public health outcomes.

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Evidence supporting the use of: Iodine
For the health condition: Goiter

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Health Concerns

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Evidence supporting the use of: IodineFor the health condition: Goiter

Table of Contents

Synopsis

Other ingredients used for Goiter

Other health conditions supported by iodine

Products containing iodine

Evidence supporting the use of: Iodine
For the health condition: Goiter