Evidence supporting the use of: Broussonetia
For the health condition: Gout

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Broussonetia, particularly Broussonetia papyrifera (paper mulberry), has been used in traditional Chinese medicine (TCM) and other East Asian herbal systems. Historical texts, such as the Chinese Pharmacopeia, mention its use in managing "wind-dampness" conditions, which can correspond to symptoms seen in gout (joint pain, swelling). Specific preparations using the leaves, bark, or root are sometimes indicated for “relieving pain” and “reducing swelling”, which are relevant to gouty arthritis. However, the scientific evidence supporting its effectiveness for gout is minimal. Only a few in vitro or animal studies have investigated the anti-inflammatory or uric acid-lowering effects of Broussonetia extracts, and these are preliminary. There are no robust clinical trials or meta-analyses confirming its efficacy or safety for gout in humans. Most contemporary sources that recommend Broussonetia for gout reference its historical use rather than any validated pharmacological mechanism. In summary, Broussonetia’s use in gout is justified by tradition, but the evidence base is weak and largely anecdotal.

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