Evidence supporting the use of: Jamaican Sarsaparilla
For the health condition: Gout

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Jamaican Sarsaparilla (Smilax regelii or related Smilax species) has a long history of use in traditional Caribbean and Central American herbal medicine, including for conditions associated with inflammation and pain such as gout. Historical records and ethnobotanical sources suggest that sarsaparilla root teas and decoctions have been used as blood purifiers and to help with rheumatic conditions, which sometimes includes gout. The rationale for its use centers on its purported anti-inflammatory properties and its ability to promote diuresis (increased urine output), potentially aiding in the elimination of uric acid, the substance that accumulates in gout. However, scientific evidence directly supporting the effectiveness of Jamaican Sarsaparilla for treating gout is very limited. While some laboratory studies have shown that certain compounds in sarsaparilla, such as saponins and flavonoids, possess anti-inflammatory activity, there are no robust clinical trials or pharmacological studies specifically investigating its impact on uric acid levels or gout symptoms in humans. Therefore, the use of Jamaican Sarsaparilla for gout is primarily based on traditional practice and anecdotal reports rather than scientific validation.

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