Evidence supporting the use of: Oregon grape
For the health condition: Gout

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Oregon grape (Mahonia aquifolium) has traditionally been used in herbal medicine for a variety of conditions, primarily for its antimicrobial, anti-inflammatory, and liver-supporting properties. Its use for gout, however, is based more on traditional herbal theory rather than robust scientific validation. In traditional herbalism, Oregon grape is considered a "blood purifier" and is believed to support detoxification pathways, including liver and kidney function, which are relevant to gout as these organs are involved in uric acid metabolism and excretion. Some herbalists have recommended Oregon grape for gout on the basis that it may help reduce systemic inflammation and improve the elimination of uric acid due to its potential diuretic and anti-inflammatory effects.

However, there is minimal direct clinical or preclinical evidence to support its efficacy specifically for gout. The plant contains berberine, an alkaloid that has demonstrated anti-inflammatory and antimicrobial properties in studies, but research on berberine for gout is lacking. Most references to Oregon grape for gout are found in traditional herbal texts or anecdotal accounts rather than controlled scientific studies. Therefore, while its use is rooted in traditional herbal practice, the evidence base is weak, and it cannot be considered a well-supported treatment for gout based on current scientific understanding.

More about oregon grape
More about Gout