Evidence supporting the use of: Prepared aconite tuber
For the health condition: Gout

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Prepared Aconite Tuber (commonly known as processed Aconitum carmichaelii or "Fu Zi") is a traditional Chinese medicinal ingredient that has been used for centuries to address conditions characterized by pain, inflammation, and "cold-damp" syndromes, which in some contexts are thought to align with the Western concept of gout. In Traditional Chinese Medicine (TCM), gout-like symptoms are often classified as "Bi syndrome," and Fu Zi is included in formulas to "warm the meridians," "dispel cold," and "alleviate pain." Historical materia medica texts such as the Shennong Bencao Jing and later TCM formularies describe the use of processed aconite in treating joint pain and swelling, which may overlap with gouty arthritis symptoms.

However, scientific validation of its efficacy and safety for gout is lacking. Preclinical studies have shown that aconite alkaloids have anti-inflammatory and analgesic effects, but these findings are not specific to gout and are overshadowed by concerns about toxicity. No rigorous clinical trials have established the effectiveness or safety of prepared aconite tuber for treating gout in humans. Modern use, therefore, relies heavily on tradition rather than robust scientific evidence. Furthermore, improper processing or dosing of aconite can lead to serious, potentially fatal toxicity. In summary, use of prepared aconite tuber for gout is primarily justified by TCM tradition rather than scientific validation, and its use should be approached with caution.

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