Relationship: Grief and Sadness and vitamin D

Evidence supporting the use of: Vitamin D
For the health condition: Grief and Sadness

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin D has been investigated for its potential role in mood regulation, including symptoms of sadness and depression, which may overlap with the emotional experiences of grief. Several observational studies have noted that individuals with low vitamin D levels are at greater risk for depressive symptoms. This has led to the hypothesis that vitamin D supplementation might improve mood or alleviate feelings associated with sadness. Some randomized controlled trials (RCTs) have shown modest improvements in depressive symptoms with vitamin D supplementation, particularly in individuals who are deficient in the vitamin. However, results are mixed—other RCTs have found little to no benefit for mood disorders or grief specifically.

The biological rationale centers on vitamin D receptors in the brain, including areas involved in mood regulation, and its possible influence on neurotransmitter synthesis. Despite these plausible mechanisms and some supportive evidence, there is not strong or consistent scientific validation for vitamin D as a treatment for grief or sadness in people with normal vitamin D levels. Most clinical guidelines do not recommend vitamin D supplementation solely for mood-related conditions unless a deficiency is present.

In summary, while there is some scientific interest and preliminary evidence linking vitamin D and mood, the overall quality and consistency of the evidence is limited, warranting a modest rating (2/5). Supplementation may be helpful for those who are deficient, but it is not established as a primary treatment for grief or sadness.

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Evidence supporting the use of: Vitamin D
For the health condition: Grief and Sadness

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Evidence supporting the use of: Vitamin DFor the health condition: Grief and Sadness

Table of Contents

Synopsis

Other ingredients used for Grief and Sadness

Other health conditions supported by vitamin D

Products containing vitamin D

Evidence supporting the use of: Vitamin D
For the health condition: Grief and Sadness