Evidence supporting the use of: Bioflavonoids (mixed)
For the body system: Gums

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bioflavonoids (also called flavonoids) are a diverse group of plant compounds commonly found in fruits and vegetables, especially citrus fruits. Their use to support gum health is primarily justified by scientific research, though the strength of the evidence is modest. Bioflavonoids are known for their antioxidant and anti-inflammatory properties, which are relevant to gum (periodontal) health. Several studies have investigated the potential of bioflavonoids to reduce gingival inflammation and improve capillary strength, which may help reduce bleeding gums and improve overall gum health.

For example, hesperidin, rutin, and quercetin—common bioflavonoids—have demonstrated the ability to inhibit the growth of oral pathogens and reduce inflammatory markers in laboratory and animal studies. Some small human studies and clinical trials have shown that supplementation with bioflavonoids (often in combination with vitamin C) can decrease gum bleeding and signs of gingivitis, though results are not universally consistent and sample sizes are often small. The theoretical basis is that bioflavonoids may strengthen connective tissue, reduce permeability and fragility of capillaries, and modulate the immune response in the gums.

However, more robust, large-scale clinical trials are needed to establish clear efficacy. Current evidence supports a modest benefit of bioflavonoids for gum health, justifying their use to a degree, but not as a primary or sole intervention for gum disease.

More about Bioflavonoids (mixed)
More about Gums

Other body systems supported by Bioflavonoids (mixed)

Arteries
Blood
Capillaries
Circulatory System
Eyes
Gums
Heart
Immune System
Skin
Veins

Products containing Bioflavonoids (mixed)

We currently have no products on Vitabase that contain this ingredient.