Evidence supporting the use of: Bioflavonoids (mixture)
For the body system: Gums

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bioflavonoids are a class of plant-derived compounds often found in citrus fruits and are sometimes recommended as supplements for gum health. The rationale for their use is primarily based on their antioxidant and anti-inflammatory properties. Some small clinical studies and preclinical research suggest that bioflavonoids, particularly when combined with vitamin C, may help reduce gum bleeding, inflammation, and capillary fragility—factors relevant to periodontal (gum) health. For example, studies from the mid-20th century reported improvements in gingival bleeding with bioflavonoid supplementation, though these studies often had methodological limitations such as small sample sizes and lack of blinding or placebo controls.

More recent laboratory studies indicate that bioflavonoids can inhibit the growth of certain oral pathogens and reduce inflammatory responses in gum tissues. However, direct, large-scale, high-quality clinical trials assessing their efficacy for treating or preventing periodontal disease are lacking. Major dental and medical organizations do not currently endorse bioflavonoids as a standard therapy for gum disease, and systematic reviews identify the evidence as insufficient to draw firm conclusions.

In summary, while there is some scientific rationale and limited clinical evidence supporting bioflavonoids for gum health, the overall evidence base is weak and not definitive. Their use is thus supported by low-to-moderate quality scientific evidence, reflected in a rating of 2 out of 5.

More about Bioflavonoids (mixture)
More about Gums

Other body systems supported by Bioflavonoids (mixture)

Arteries
Blood
Capillaries
Circulatory System
Eyes
Gums
Heart
Immune System
Liver
Skin
Veins

Products containing Bioflavonoids (mixture)

We currently have no products on Vitabase that contain this ingredient.