Evidence supporting the use of: Coenzyme Q10 (CoQ10)
For the body system: Gums

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Coenzyme Q10 (CoQ10) is an antioxidant that plays a crucial role in cellular energy production. Its use to support gum (periodontal) health has some scientific validation. Several studies have explored the potential benefits of CoQ10 in the management of periodontal disease—a chronic inflammatory condition affecting the gums and supporting structures of the teeth. Some clinical trials and reviews suggest that CoQ10, when applied topically or taken orally as a supplement, may help reduce inflammation and improve healing in patients with periodontal disease. The proposed mechanism involves CoQ10’s role in enhancing cellular energy metabolism and its antioxidant properties, which may help counteract oxidative stress in gum tissues.

A 2015 review published in the Journal of Clinical and Diagnostic Research found that topical application of CoQ10 could be beneficial as an adjunct to conventional periodontal therapy, potentially improving clinical parameters such as pocket depth and gum bleeding. However, the evidence base is limited by small sample sizes and methodological differences among studies. Systematic reviews, including one from 2022, generally conclude that while there is promising evidence, more rigorous and larger-scale studies are needed to confirm the effectiveness of CoQ10 for gum health.

Overall, CoQ10 is used for supporting gum health based on moderate scientific evidence, but it is not yet a standard treatment. Users considering CoQ10 for periodontal support should consult with dental or healthcare professionals.

More about coenzyme Q10 (CoQ10)
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Other ingredients that support Gums

Acacia
Agonandra
Agrimonia pilosa
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Alchemilla
Alkanna
Allicin
Allspice
Aloe vera
anthocyanins
apple
apple cider vinegar
Areca
Ascophyllum nodosum
asiaticoside
aucubin
avens
Baccharis dracunculifolia
bai ji
balsam
bayberry
bee products
bee propolis
benzoin
berry
betel
betony
bilberry
bioflavonoids
bistort
blackberry
Bletilla
bloodroot
Boswellia
Brazilian peppertree
cajuput
Calendula
Calycophyllum
canaigre
capsicum
cardamom
carvacrol
Casearia sylvestris
catechins
catechu
cayenne pepper
cinquefoil
Cistus
Citrus
citrus bioflavonoids
citrus sinensis (proprietary)
clove
coca
coenzyme Q10 (CoQ10)
collagen
Collinsonia
comfrey
commiphora
cranesbill
Curcuma
curcumin
Curcuminoid
cutch
Cyanthillium cinereum
dragon\'s blood
Drynaria
Echinacea
emblicanin
eugenol
European five-finger grass
fiber
flavanones
flavans
flavonoids
flavonols
flavonones
fleabane
fluoride
fluorine
frankincense
fructoborate
Gambir
garlic
Glechoma hederacea
goldenseal
goldenseal
goldthread
gooseberry
Guava
heal-all
Heliopsis
henna
herbal blend (proprietary)
hesperidin
honey
horsetail
hyaluronic acid
Indian frankincense
Indian kinotree
Jaboticaba
Kigelia africana
Lactobacillus reuteri
Lactobacillus salivarius
Lactoperoxidase
Lady's Mantle
lemon
Leptospermum scoparium
leucoanthocyanidins
licorice root
lime
lingonberry
lodhtree
lysozyme
Mahonia
mallow
Malva sylvestris
mango
manzanita
marigold
Marking Nut Tree
Marshmallow
Massularia acuminata
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Matico
melaleuca alternifolia
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Mineral ascorbate
mixed carotenoids
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Myrrh
Nasturtium
Neem tree
New Jersey Tea
Nimbidin
Oak
Oleuropein
Oligomeric proanthocyanidins
omega-3 fatty acids
orange
oregon grape
Orris
Pacific madrone
pagoda tree
Pedra hume
Pellitory
Persimmon
phenolic compounds
Phosphate ascorbate
pine bark
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plantain
polyphenols
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prickly ash
proanthocyanidins
procyanidin
procyanidol
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punicalagins
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sage
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shepherd's purse
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slippery elm bark
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Terminalia
Thymol
Toothache Plant
Tridax
Triphala
turmeric
Ulmus
Vestitol
vitamin C
vitamin K
Water Pepper
White oak
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white willow
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zanthoxylum
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Products containing coenzyme Q10 (CoQ10)

Pure Encapsulations Athletic Nutrients
Douglas Laboratories Citrus-Q10 ™
Douglas Laboratories Co-Enzyme Q10 Softgel
Douglas Laboratories Coenzyme Q-10 with Lipoic Acid
Douglas Laboratories Coenzyme Q-10 with Lipoic Acid
Integrative Therapeutics CoQ10
Integrative Therapeutics COQ10 100 mg Tropical
Pure Encapsulations CoQ10 120 mg
Pure Encapsulations CoQ10 120 mg
Pure Encapsulations CoQ10 120 mg
Integrative Therapeutics COQ10 200 mg Chocolate 30 chew tabs
Pure Encapsulations CoQ10 250 mg
Pure Encapsulations CoQ10 30 mg
Pure Encapsulations CoQ10 500 mg
Pure Encapsulations CoQ10 60 mg
Pure Encapsulations CoQ10 60 mg
Pure Encapsulations CoQ10 60 mg
Pure Encapsulations CoQ10 l-Carnitine Fumarate
Thorne CoQ10 Q-Best 100
Metagenics CoQ10 ST®-100 mg
Metagenics CoQ10 ST-100 mg
Metagenics CoQ10 ST-200 mg
Integrative Therapeutics Detoxication Factors
Integrative Therapeutics Detoxication Factors
Pure Encapsulations Energize Plus™ Pure Pack
Pure Encapsulations Hair/Skin/Nails Ultra
Thorne Heart Health Complex Q-10 Plus
Integrative Therapeutics K-PAX MitoNutrients
Vitabase Life's Essentials Plus
Designs For Health Mito-NR™
Pure Encapsulations Mitochondria-ATP
Designs For Health Mitochondrial NRG™
Pure Encapsulations NeuroMood Pure Pack
Metagenics NutraGems® CoQ10 300
Pure Encapsulations O.N.E.™ Multivitamin
Pure Encapsulations O.N.E.™ Multivitamin
Pure Encapsulations O.N.E.™ Multivitamin
Thorne Omega-3 w/ CoQ10
Thorne Ovarian Care
Integrative Therapeutics ProThrivers Wellness Flav Complex
Pure Encapsulations PureGenomics® UltraMultivitamin
Designs For Health Q-Evail® 100
Designs For Health Q-Evail® 200
Pure Encapsulations Q-Gel® (Hydrosoluble™ CoQ10) 100 mg
Thorne Red Yeast Rice + CoQ10 Choleast
Pure Encapsulations Renual
Pure Encapsulations RevitalAge™ Nerve
Pure Encapsulations RevitalAge™ Ultra
Designs For Health RYR Synergy™
Pure Encapsulations SR-CoQ10 with PQQ
Vitabase Super Fat Burner
Pure Encapsulations Ubiquinol-QH 100 mg
Pure Encapsulations Ubiquinol-QH 200 mg
Pure Encapsulations Ubiquinol VESIsorb®
Integrative Therapeutics UBQH 100 mg
Douglas Laboratories Ultra Preventive 50+ -EZ Swallow
Douglas Laboratories Ultra Preventive One Daily
Pure Encapsulations Ultra Pure Pack
Pure Encapsulations UltraDetox 10-Day Pure Pack
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Metagenics Wellness Essentials Brain Health Daily Packs