Flavonoids are a diverse group of plant compounds known for their antioxidant and anti-inflammatory properties. There is scientific evidence supporting the role of flavonoids in gum (periodontal) health. Clinical studies and laboratory research suggest that flavonoids can inhibit the growth of bacteria associated with periodontal disease, reduce inflammation, and help protect gum tissues from oxidative stress. For example, quercetin, catechins (found in green tea), and hesperidin are flavonoids that have demonstrated beneficial effects on gum health in various studies. These compounds may reduce bleeding, swelling, and pocket depth in the gums, which are common markers of gum disease. Additionally, some studies have shown that mouthwashes or toothpastes containing flavonoid-rich extracts can improve periodontal outcomes when used alongside standard oral hygiene practices.

However, while the evidence is promising, it is not yet conclusive. Most studies are small or short-term, and flavonoids are usually studied as part of a broader intervention rather than as isolated compounds. As a result, flavonoids receive a moderate evidence rating (3/5) for supporting gum health. Their use is grounded in scientific research but is not yet universally accepted in clinical guidelines. Ongoing research may further clarify the extent of their benefits for maintaining healthy gums.