Evidence supporting the use of: Flavonones
For the body system: Gums

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Flavanones, a subclass of flavonoids commonly found in citrus fruits, have been investigated for their potential benefits in supporting oral and gum health. Scientific evidence suggests that flavanones such as hesperidin and naringenin possess anti-inflammatory, antioxidant, and antimicrobial properties, which may contribute to maintaining healthy gums. Several in vitro and animal studies have demonstrated that flavanones can inhibit the growth of oral pathogens associated with periodontal disease, reduce inflammation in gingival tissues, and protect against oxidative stress-induced damage in oral cells.

Human studies are more limited but promising. For example, some clinical trials have shown that mouthwashes or oral supplements containing citrus flavonoids can reduce gingival bleeding, plaque buildup, and markers of inflammation in patients with gingivitis. However, these studies often involve small sample sizes or are combined with other active ingredients, making it difficult to isolate the effects of flavanones alone. Systematic reviews acknowledge the potential for flavonoids, including flavanones, to support oral health but emphasize the need for larger, well-designed clinical trials to establish definitive efficacy.

In summary, while the use of flavanones for gum health is supported by some scientific evidence—primarily in laboratory and early clinical studies—more robust research is needed. The current evidence base justifies a moderate rating for scientific support in the context of gum health.

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