Evidence supporting the use of: Lysozyme
For the body system: Gums

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lysozyme is an enzyme with antimicrobial properties that is naturally present in human saliva, tears, and other secretions. Its primary function is to break down the cell walls of certain bacteria, contributing to the body's innate immune defense. Scientific studies have explored lysozyme’s role in oral health, particularly in the context of gum (periodontal) health. Research has shown that lysozyme can inhibit the growth of oral pathogens such as Streptococcus mutans and Porphyromonas gingivalis, both implicated in dental plaque formation and periodontal disease. Some clinical trials and in vitro studies suggest that lysozyme-containing oral care products (such as toothpastes or mouthwashes) may help reduce plaque accumulation and support gum health by limiting bacterial colonization. However, the overall quality and quantity of clinical evidence is moderate, with most studies being small or not directly measuring clinical endpoints like reduced gingivitis or periodontitis. Despite this, the biological plausibility and preliminary findings provide a reasonable scientific basis for the use of lysozyme in supporting gum health, though it should not be considered a substitute for standard oral hygiene practices. Further large-scale, well-designed clinical trials are needed to fully establish its efficacy for this purpose.

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