Evidence supporting the use of: Mixed carotenoids
For the body system: Gums

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Mixed carotenoids, which include compounds such as beta-carotene, lutein, zeaxanthin, and lycopene, are antioxidants widely found in fruits and vegetables. Their use for supporting gum (periodontal) health is based on both their antioxidant properties and a limited but growing body of scientific research. Oxidative stress and inflammation are recognized contributors to periodontal disease, and antioxidants like carotenoids may help mitigate these processes. Some clinical studies have observed that individuals with higher dietary intake or blood levels of carotenoids, particularly beta-carotene and lycopene, may have a reduced risk of periodontal disease or less severe gum inflammation. For example, a few observational studies have found inverse associations between serum carotenoid levels and prevalence of periodontitis. However, intervention studies directly supplementing carotenoids and measuring clinical gum health outcomes are limited, and results are not yet conclusive or robust. Overall, while there is some scientific rationale and preliminary evidence supporting the use of mixed carotenoids for gum health, the evidence base is not strong or definitive. More high-quality, controlled clinical trials are needed to establish clear benefits. For now, mixed carotenoids may play a supportive role as part of a diet rich in fruits and vegetables, but should not be relied upon as a primary therapy for gum disease.

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