Oleuropein is a polyphenolic compound found in olives and olive leaves and has been researched for various health effects, including antimicrobial and anti-inflammatory properties. In the context of gum (periodontal) health, some scientific studies suggest that oleuropein may be beneficial. In vitro studies have shown that oleuropein can inhibit the growth of several oral pathogens, including Porphyromonas gingivalis and Streptococcus mutans, which are implicated in gum disease and dental caries. Additionally, animal studies have demonstrated anti-inflammatory effects that could theoretically reduce periodontal tissue inflammation.

However, while these findings are promising, the majority of evidence is preclinical (cell culture and animal studies), with limited direct evidence from human clinical trials specifically examining oleuropein for gum health. Existing human studies on olive leaf extracts (which contain oleuropein) often focus on general oral health or unrelated health parameters. Thus, while there is a scientific rationale for its use, and preliminary laboratory evidence supports its antibacterial and anti-inflammatory effects relevant to gum health, robust clinical validation is lacking.

In summary, the use of oleuropein for supporting gum health is supported by early-stage scientific data, but more high-quality human studies are needed to confirm its efficacy in this context.