Evidence supporting the use of: Oligomeric proanthocyanidins
For the body system: Gums

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Oligomeric proanthocyanidins (OPCs) are a class of polyphenolic compounds found in foods such as grapes, cranberries, and pine bark. Their use for supporting gum (periodontal) health is primarily based on scientific evidence, though the body of research is still developing. In vitro and animal studies have demonstrated that OPCs possess potent antioxidant and anti-inflammatory properties, which are beneficial for oral tissues. Specifically, OPCs have been shown to inhibit the growth of oral pathogens such as Porphyromonas gingivalis, a key bacterium involved in periodontal disease. OPCs also help stabilize collagen, an important protein in gum tissue, and may promote tissue repair.

Some small clinical studies suggest that OPC supplementation can reduce signs of gingival inflammation and bleeding in individuals with gum disease. For instance, pine bark extract (rich in OPCs) has been reported to improve periodontal parameters such as bleeding on probing and pocket depth when used as an adjunct to conventional dental care. However, more large-scale, high-quality clinical trials are needed to draw definitive conclusions regarding effectiveness and optimal dosing. Overall, while traditional use is limited, the scientific evidence provides a moderate level of support for OPCs in promoting gum health.

More about Oligomeric proanthocyanidins
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Other ingredients that support Gums

Acacia
Agonandra
Agrimonia pilosa
Agrimony
Alchemilla
Alkanna
Allicin
Allspice
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anthocyanins
apple
apple cider vinegar
Areca
Ascophyllum nodosum
asiaticoside
aucubin
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Baccharis dracunculifolia
bai ji
balsam
bayberry
bee products
bee propolis
benzoin
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betel
betony
bilberry
bioflavonoids
bistort
blackberry
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bloodroot
Boswellia
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cajuput
Calendula
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canaigre
capsicum
cardamom
carvacrol
Casearia sylvestris
catechins
catechu
cayenne pepper
cinquefoil
Cistus
Citrus
citrus bioflavonoids
citrus sinensis (proprietary)
clove
coca
coenzyme Q10 (CoQ10)
collagen
Collinsonia
comfrey
commiphora
cranesbill
Curcuma
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cutch
Cyanthillium cinereum
dragon\'s blood
Drynaria
Echinacea
emblicanin
eugenol
European five-finger grass
fiber
flavanones
flavans
flavonoids
flavonols
flavonones
fleabane
fluoride
fluorine
frankincense
fructoborate
Gambir
garlic
Glechoma hederacea
goldenseal
goldenseal
goldthread
gooseberry
Guava
heal-all
Heliopsis
henna
herbal blend (proprietary)
hesperidin
honey
horsetail
hyaluronic acid
Indian frankincense
Indian kinotree
Jaboticaba
Kigelia africana
Lactobacillus reuteri
Lactobacillus salivarius
Lactoperoxidase
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lemon
Leptospermum scoparium
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licorice root
lime
lingonberry
lodhtree
lysozyme
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mallow
Malva sylvestris
mango
manzanita
marigold
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melaleuca alternifolia
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Oak
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Oligomeric proanthocyanidins
omega-3 fatty acids
orange
oregon grape
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pagoda tree
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plantain
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sage
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shepherd's purse
Silverweed
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Tridax
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turmeric
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Vestitol
vitamin C
vitamin K
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White Tea
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Other body systems supported by Oligomeric proanthocyanidins

Arteries
Blood
Brain
Capillaries
Circulatory System
Eyes
Gums
Heart
Immune System
Skin
Veins

Products containing Oligomeric proanthocyanidins

We currently have no products on Vitabase that contain this ingredient.