Evidence supporting the use of: Proanthocyanidins (unspecified)
For the body system: Gums

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Proanthocyanidins are a class of polyphenolic compounds found abundantly in foods such as grapes, cranberries, and cocoa. Their use to support gum (periodontal) health has some scientific validation. Several in vitro and animal studies have demonstrated that proanthocyanidins possess anti-inflammatory, antioxidant, and antimicrobial properties, which can be beneficial in reducing the bacterial load and inflammation associated with periodontal disease. For example, proanthocyanidins from cranberries have been shown to inhibit the adhesion of Porphyromonas gingivalis, a key periodontal pathogen, to oral surfaces, potentially reducing plaque formation and gum disease progression. Additionally, some human clinical studies have suggested that supplements or rinses containing proanthocyanidins may reduce gingival bleeding and inflammation, although these studies tend to be small and of varying methodological quality.

While the evidence is not yet definitive and more large-scale, well-designed clinical trials are needed, the biological plausibility and preliminary research support the potential for proanthocyanidins to contribute to gum health. Thus, their use is justified by emerging scientific findings, although not yet considered a gold-standard therapy. Traditional use is less prominent, as the focus on proanthocyanidins for oral health is a relatively recent development in nutritional and dental science.

More about Proanthocyanidins (unspecified)
More about Gums

Other body systems supported by Proanthocyanidins (unspecified)

Arteries
Blood
Capillaries
Circulatory System
Gums
Heart
Immune System
Skin
Urinary System
Veins

Products containing Proanthocyanidins (unspecified)

We currently have no products on Vitabase that contain this ingredient.