Evidence supporting the use of: Procyanidin (unspecified)
For the body system: Gums
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Procyanidins are a class of polyphenolic compounds found in many plants, notably in grape seeds, cranberries, and cocoa. Their use for supporting the gums primarily stems from their well-documented antioxidant and anti-inflammatory properties. Several in vitro and animal studies have demonstrated that procyanidins can inhibit the growth of periodontal pathogens and reduce inflammation in gum tissues. For example, grape seed procyanidins have been shown to suppress the expression of inflammatory cytokines and matrix metalloproteinases involved in gum disease progression. Additionally, these compounds may enhance collagen synthesis and stability, contributing to healthier connective tissue in the gums.
While the majority of evidence comes from laboratory and animal research, a few small-scale human studies have suggested a potential benefit of procyanidin-containing extracts in reducing gingival inflammation and improving periodontal parameters. However, robust, large-scale clinical trials are lacking. Thus, while there is promising preliminary scientific evidence supporting the use of procyanidins for gum health, more research is needed to firmly establish their efficacy in humans.
Other ingredients that support Gums
cutchallspice
aloe vera
anthocyanins
apple
bayberry
beeswax
myrobalan
betel
bilberry
bisabolol
blackberry
Indian frankincense
bovine gelatin
catechins
citrus bioflavonoids
citrus sinensis (proprietary)
clove
coenzyme Q10 (CoQ10)
collagen
turmeric
curcumin
flavonols
gelatin
goldenseal
goldenseal
gooseberry
gum ghatti
hesperidin
horsetail
hyaluronic acid
lactobacillus reuteri
lactobacillus salivarius
lactoperoxidase
lemon
licorice root
mango
marshmallow
mastic gum
mixed carotenoids
omega-3 fatty acids
orange
oregon grape
phenolic acids
pine bark
plantain
raspberry
rose hips
sage
slippery elm bark
triphala
vitamin C
vitamin K
white willow
xanthan gum
xylitol
zinc
yellow root
cardamom
capsicum
neem tree
pterocarpus marsupium
commiphora
yarrow
prickly ash
myrrh
zanthoxylum
polyphenols
menthol oil
shepherd's purse
white oak
herbal blend (proprietary)
melaleuca alternifolia
cayenne pepper
Avens
Apple Cider Vinegar
Asiaticoside
acacia
Agrimony
Allicin
Alchemilla
Aucubin
Ascophyllum nodosum
Areca
Agonandra
Agrimonia pilosa
Alkanna
Bee Propolis
Betony
Bai Ji
Balsam
Bistort
Baccharis dracunculifolia
Brazillian peppertree
Bloodroot
Benzoin
berry
Boswellia
Bletilla
Bioflavonoids
Bee products
Comfrey
Calendula
Carvacrol
Cinquefoil
Curcuminoid
Citrus
Cajuput
Canaigre
Catechu
Coca
Cistus
Curcuma
Cranesbill
Cyanthillium cinereum
Collinsonia
Casearia sylvestris
Calycophyllum
Drynaria
Dragon's Blood
Echinacea
Emblicanin
European-Five Finger Grass
Eugenol
Fiber
Flavonoids
Fluoride
Fluorine
Flavonones
Goldthread
Garlic
Mallow
Oak
Other body systems supported by Procyanidin (unspecified)
ArteriesBlood
Brain
Capillaries
Circulatory System
Gums
Heart
Immune System
Skin
Veins