Evidence supporting the use of: Procyanidin
For the body system: Gums

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Procyanidins are a class of polyphenolic compounds found in many plants, notably in grape seeds, cranberries, and cocoa. Their use for supporting the gums primarily stems from their well-documented antioxidant and anti-inflammatory properties. Several in vitro and animal studies have demonstrated that procyanidins can inhibit the growth of periodontal pathogens and reduce inflammation in gum tissues. For example, grape seed procyanidins have been shown to suppress the expression of inflammatory cytokines and matrix metalloproteinases involved in gum disease progression. Additionally, these compounds may enhance collagen synthesis and stability, contributing to healthier connective tissue in the gums.

While the majority of evidence comes from laboratory and animal research, a few small-scale human studies have suggested a potential benefit of procyanidin-containing extracts in reducing gingival inflammation and improving periodontal parameters. However, robust, large-scale clinical trials are lacking. Thus, while there is promising preliminary scientific evidence supporting the use of procyanidins for gum health, more research is needed to firmly establish their efficacy in humans.

More about procyanidin
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Products containing procyanidin

We currently have no products on Vitabase that contain this ingredient.