Evidence supporting the use of: Procyanidol
For the body system: Gums

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Procyanidol, more commonly known as procyanidins or oligomeric proanthocyanidins (OPCs), are a class of polyphenolic compounds found in various plants, such as grape seeds, pine bark, and cranberries. There is some scientific evidence supporting their use in oral health, specifically for the gums. Studies have indicated that procyanidins possess antioxidant, anti-inflammatory, and antimicrobial properties. These actions are relevant to periodontal health, as gum disease is characterized by inflammation and microbial infection.

In vitro and animal studies have shown that procyanidins can inhibit the growth of certain oral pathogens and reduce inflammation in gum tissues. Limited clinical research suggests that formulations containing procyanidins may help reduce gingival bleeding and improve clinical markers of gum health, although the quality and size of these studies are modest. For example, some studies on grape seed extract report reduced gum inflammation and improved healing in periodontal disease models, but robust, large-scale human trials are lacking.

Overall, while there is a scientific basis for procyanidins' potential benefit in supporting gum health, the direct clinical evidence remains limited and preliminary. The rating of 2 reflects that, although some scientific data exist, it is not yet strong or conclusive. Further well-designed human studies are required to more firmly establish procyanidins’ efficacy for supporting the gums.

More about Procyanidol
More about Gums

Other body systems supported by Procyanidol

Arteries
Capillaries
Circulatory System
Eyes
Gums
Veins

Products containing Procyanidol

We currently have no products on Vitabase that contain this ingredient.