Pycnogenol, a standardized extract from the bark of the French maritime pine tree (Pinus pinaster), has been investigated for its potential benefits in supporting gum (periodontal) health. Several clinical studies have examined its effects on periodontal disease and oral inflammation, largely due to its potent antioxidant and anti-inflammatory properties.

A notable randomized controlled trial published in 2013 in the Journal of Oral Health and Dental Management demonstrated that supplementation with Pycnogenol (50 mg twice daily for 14 days) significantly reduced gingival bleeding and improved markers of periodontal health compared to placebo. Other studies have also observed reductions in gum bleeding and improvements in periodontal indices among individuals using Pycnogenol supplements or oral rinses.

The proposed mechanisms involve Pycnogenol's ability to scavenge free radicals, inhibit inflammatory mediators, and promote microcirculation in gum tissues, which may help decrease inflammation and improve healing. However, while the evidence is promising, the number of high-quality, large-scale human trials is still limited, and most studies have relatively short durations and small sample sizes.

In summary, there is emerging scientific evidence supporting Pycnogenol's use for gum health, but further large-scale and long-term trials are needed to confirm its efficacy and establish optimal dosage protocols.