Sangre de Grado (also known as Dragon’s Blood, derived from the sap of Croton lechleri) has a long history of traditional use among indigenous peoples in the Amazon basin, particularly for wound healing, digestive issues, and oral health including gum problems. For centuries, local populations have used the sap directly on wounds, sores, and inflamed gums to promote healing and reduce discomfort. The rationale for its use in gum health comes primarily from its astringent properties, which help tighten tissue and reduce bleeding, as well as anecdotal reports of antimicrobial effects.

Scientific studies have identified that Sangre de Grado contains compounds like proanthocyanidins and taspine, which may contribute to its healing effects. Some laboratory and animal studies suggest antibacterial and anti-inflammatory activity, which could theoretically benefit gum health. However, rigorous human clinical trials specifically evaluating its efficacy for gingivitis, periodontitis, or general gum support are lacking. The available evidence is mostly preclinical or based on traditional use, with only a few small-scale human studies for other uses (such as wound healing and diarrhea). Therefore, while the traditional use is well established, scientific evidence for its effectiveness specifically in gum health remains limited.