Evidence supporting the use of: Yellow root
For the body system: Gums

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Yellow root (Xanthorhiza simplicissima), also known for its high berberine content, has a long history of traditional use by Native American and Appalachian herbalists for oral health, including supporting gum health. Traditionally, yellow root was chewed or used as a mouth rinse for its purported ability to soothe inflamed gums, treat mouth ulcers, and address infections in the mouth. The main active compound, berberine, is known for its antimicrobial and anti-inflammatory properties, which likely contributed to its application in oral care before the advent of modern dental hygiene products. While there is substantial ethnobotanical documentation of yellow root’s use for gum and oral health, direct scientific studies specifically examining yellow root for gum health are limited. However, related herbs containing berberine, such as goldenseal (Hydrastis canadensis), have been more directly studied for their effects on oral pathogens and have shown some potential in reducing plaque and gingivitis. Overall, the traditional use of yellow root for supporting the gums is well-documented, but scientific validation specific to yellow root and gum health is lacking, and the evidence relies primarily on traditional knowledge and extrapolation from studies on berberine-containing plants.

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