Evidence supporting the use of: Methylsulfonylmethane (MSM)
For the body system: Hair
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Methylsulfonylmethane (MSM) is a sulfur-containing compound that has gained popularity as a dietary supplement for supporting hair health. The rationale for its use is largely based on the importance of sulfur in the formation of keratin, the primary protein in hair. Several small-scale scientific studies and preclinical trials suggest that MSM may have a beneficial effect on hair growth and health. For example, a pilot clinical study published in 2009 found that a supplement containing MSM and other nutrients improved hair appearance and volume in participants. Additionally, an animal study (2012) noted increased hair growth in mice supplemented with MSM.
However, robust clinical data are lacking. Most studies to date are limited by small sample sizes, lack of control groups, or the use of multi-ingredient supplements (making it difficult to attribute effects solely to MSM). There is some mechanistic plausibility, since sulfur is a key component of keratin, but high-quality, large-scale human trials are needed to confirm efficacy.
In summary, while there is preliminary scientific support for the use of MSM to support hair health, the current evidence is limited and not definitive. The use of MSM for this purpose is based more on mechanistic reasoning and early clinical data rather than established, large-scale scientific validation.
Other ingredients that support Hair
amino acidsashwagandha
bamboo
biotin
bovine gelatin
ceramides
collagen
copper
fish oil
fish protein
gamma linolenic acid (GLA)
gelatin
ginseng
gooseberry
gotu kola
horsetail
iron
kelp
L-cysteine
L-cystine
L-lysine
L-methionine
L-proline
Methylsulfonylmethane (MSM)
Nettle
omega-3 fatty acids
omega-6 fatty acids
PABA (para-aminobenzoic acid)
pantothenic acid (vitamin B5)
pollen
polypeptide complex (proprietary)
protein
pumpkin
riboflavin (vitamin B2)
rosemary
sage
saw palmetto
selenium
silicon
keratin
vitamin A
vitamin B
vitamin B12
vitamin B6
vitamin C
vitamin D
vitamin E
seaweed
Zinc
Zinc
lingzhi
sunflower
trace minerals
wheat germ
herbal blend (proprietary)
Algae
bladderwrack
argan nut oil
Alkanna
animal protein
black seed
babchi
beef
Beef liver
bovine protein
curry leaf
Cetearyl alcohol
Chinese fleeceflower
Cymbopogon martini
castile soap
Cystine
DL-Methionine
Drynaria
egg
Eclipta
emu oil
Egg protein
ferritin
fo-ti
fish
fatty acids
Growth factors
garden cress
henna
jojoba oil
lipids
Molasses
Miliacin
Marine protein
Maidenhair Fern
Nigella seed
Panthenol
Polygonum
Peptides
Quinoa Protein
Selenomethionine
Silk protein
Salmon Oil
Sapindus mukorossi
Sulfur
silica
Tridax
Tea Tree Oil
Vegetable Protein
Other body systems supported by Methylsulfonylmethane (MSM)
HairImmune System
Joints
Muscles
Skin
Structural System
Products containing Methylsulfonylmethane (MSM)
Designs For Health
Amino-D-Tox™
Designs For Health
Amino-D-Tox™
Designs For Health
ArthroSoothe™
Designs For Health
ArthroSoothe™ Supreme
Metagenics
ChondroCare®
Metagenics
Collagenics®
Designs For Health
GI Revive®
Designs For Health
GI Revive®
Vitabase
Glucosamine / Chondroitin / MSM
Pure Encapsulations
Glucosamine Chondroitin with MSM
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Glucosamine Chondroitin with MSM
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Glucosamine Chondroitin with MSM
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Glucosamine Chondroitin with MSM
Douglas Laboratories
Glucosamine + MSM Forte ™
Pure Encapsulations
Glucosamine/MSM with Joint Comfort Herbs
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Glucosamine/MSM with Joint Comfort Herbs
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Glucosamine Plus ™
Vitabase
Hair, Skin & Nails Formula
Pure Encapsulations
Joint Complex
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Joint Complex
Thorne
Joint Support Nutrients AR-Encap
Thorne
MediClear Plus
Pure Encapsulations
MSM
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MSM
Douglas Laboratories
MSM Capsules
Pure Encapsulations
MSM Powder
Designs For Health
PaleoCleanse Plus™
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PaleoCleanse Plus™
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PaleoCleanse Plus™ Detox Program
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PaleoCleanse Plus™Chocolate Detox Kit
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Plant Protein Cleanse
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Plant Protein Cleanse Plus™ 570g
Metagenics
Wellness Essentials Active Daily Packs