Evidence supporting the use of: Methylsulfonylmethane (MSM)
For the body system: Hair

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Methylsulfonylmethane (MSM) is a sulfur-containing compound that has gained popularity as a dietary supplement for supporting hair health. The rationale for its use is largely based on the importance of sulfur in the formation of keratin, the primary protein in hair. Several small-scale scientific studies and preclinical trials suggest that MSM may have a beneficial effect on hair growth and health. For example, a pilot clinical study published in 2009 found that a supplement containing MSM and other nutrients improved hair appearance and volume in participants. Additionally, an animal study (2012) noted increased hair growth in mice supplemented with MSM.

However, robust clinical data are lacking. Most studies to date are limited by small sample sizes, lack of control groups, or the use of multi-ingredient supplements (making it difficult to attribute effects solely to MSM). There is some mechanistic plausibility, since sulfur is a key component of keratin, but high-quality, large-scale human trials are needed to confirm efficacy.

In summary, while there is preliminary scientific support for the use of MSM to support hair health, the current evidence is limited and not definitive. The use of MSM for this purpose is based more on mechanistic reasoning and early clinical data rather than established, large-scale scientific validation.

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Other body systems supported by methylsulfonylmethane (MSM)

Hair
Immune System
Muscles
Skin
Structural System
Joints