Evidence supporting the use of: Selenomethionine
For the body system: Hair

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Selenomethionine is a major dietary form of selenium, an essential trace mineral with important biological roles. Its use to support the hair system is scientifically justified primarily due to selenium’s established function in maintaining hair follicle health. Selenium is a critical component of antioxidant enzymes such as glutathione peroxidases, which protect cells—including those in the scalp and hair follicles—from oxidative stress. Several studies have shown that selenium deficiency can result in hair loss, as well as other issues like depigmentation and delayed hair growth. For example, animal studies have demonstrated that selenium deficiency leads to hair loss and skin lesions, which are reversed when selenium is reintroduced into the diet. In humans, severe selenium deficiency is rare, but some case reports and population studies have suggested a link between inadequate selenium status and alopecia (hair loss).

However, while selenium is essential, there is limited evidence that supplementing selenomethionine beyond the recommended dietary allowance promotes additional hair growth or prevents hair loss in those without deficiency. Some shampoos and supplements include selenium compounds, but robust clinical trials documenting effectiveness for hair growth in healthy individuals are lacking. Excessive selenium intake can also be toxic and lead to hair loss. Thus, while the rationale for using selenomethionine to support hair health is grounded in basic nutritional science, the evidence for benefit in well-nourished individuals is moderate rather than strong.

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