Evidence supporting the use of: Cystine
For the health condition: Hair (loss or thinning)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Cystine is an amino acid that forms from two cysteine molecules linked by a disulfide bond. Its use in supporting hair growth or treating hair loss/thinning is rooted primarily in tradition and the biochemical role of cystine in keratin structure. Hair is composed largely of keratin, a protein rich in cystine-derived disulfide bridges, which contribute to hair’s strength and rigidity. Because of this, cystine has historically been included in hair supplements and “hair tonic” formulations, with the rationale that providing more of this amino acid might support hair health.
However, scientific evidence directly supporting cystine supplementation for hair loss or thinning in otherwise healthy individuals is limited and not robust. Some small studies and anecdotal reports suggest possible benefits when cystine is combined with other nutrients (such as B vitamins or medicinal yeast), but these studies often have methodological weaknesses, lack controls, or use combination products, making it difficult to isolate the effect of cystine itself. There is no high-quality, large-scale clinical trial demonstrating cystine supplementation alone significantly improves hair growth or reduces hair loss. Most professional guidelines for hair loss do not include cystine as a recommended treatment.
In summary, while the use of cystine for hair health is based on a plausible biochemical rationale and historical tradition, scientific validation remains weak, and routine supplementation is not clearly supported by current evidence.
Other ingredients used for Hair (loss or thinning)
alfalfaamino acids
apricot
ashwagandha
biotin
black garlic
bovine gelatin
rice
burdock
collagen
epigallocatechin gallate (EGCG)
fish protein
flavonols
gelatin
ginseng
gooseberry
gotu kola
onion
green tea
iron
l-cystine
l-methionine
licorice root
moringa
nettle
niacinamide (vitamin B3)
omega-3 fatty acids
PABA (para-aminobenzoic acid)
pantothenic acid (vitamin B5)
pollen
protein
quail egg
quercetin
reishi mushroom
selenium
silicon
spinach
spirulina
almond fruit
vitamin A
vitamin B
vitamin B12
vitamin B6
vitamin C
vitamin D
vitamin D3
vitamin E
seaweed
zinc
bee pollen
dioscorea
ganoderma
morinda
royal jelly
trace minerals
fulvic acid
algae
thyroid substance
Argan nut oil
Animal protein
Black Seed
Babchi
Beef liver
Ba Ji Tian
Borassus aethiopum
coconut oil
Chlorophytum
Cystine
DL-Methionine
Epidermal Growth Factor
Egg
Eugenol
fibroblast growth factor
walnut