Evidence supporting the use of: Cystine
For the health condition: Hair (loss or thinning)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Cystine is an amino acid that forms from two cysteine molecules linked by a disulfide bond. Its use in supporting hair growth or treating hair loss/thinning is rooted primarily in tradition and the biochemical role of cystine in keratin structure. Hair is composed largely of keratin, a protein rich in cystine-derived disulfide bridges, which contribute to hair’s strength and rigidity. Because of this, cystine has historically been included in hair supplements and “hair tonic” formulations, with the rationale that providing more of this amino acid might support hair health.
However, scientific evidence directly supporting cystine supplementation for hair loss or thinning in otherwise healthy individuals is limited and not robust. Some small studies and anecdotal reports suggest possible benefits when cystine is combined with other nutrients (such as B vitamins or medicinal yeast), but these studies often have methodological weaknesses, lack controls, or use combination products, making it difficult to isolate the effect of cystine itself. There is no high-quality, large-scale clinical trial demonstrating cystine supplementation alone significantly improves hair growth or reduces hair loss. Most professional guidelines for hair loss do not include cystine as a recommended treatment.
In summary, while the use of cystine for hair health is based on a plausible biochemical rationale and historical tradition, scientific validation remains weak, and routine supplementation is not clearly supported by current evidence.
Other ingredients used for Hair (loss or thinning)
AlfalfaAlgae
Almond fruit
amino acids
animal protein
apricot
argan nut oil
ashwagandha
ba ji tian
babchi
bee pollen
Beef liver
biotin
black garlic
black seed
Borassus aethiopum
burdock
Chlorophytum
coconut oil
collagen
Cystine
dioscorea
DL-Methionine
egg
Epidermal Growth Factor
epigallocatechin gallate (EGCG)
eugenol
fatty acids
fibroblast growth factor
fish protein
flavonols
fo-ti
fulvic acid
ganoderma
ginseng
gooseberry
gotu kola
green tea
iron
Kokilaksha
L-cystine
L-methionine
licorice root
lipids
Lycium
Morinda
Moringa
Nettle
Niacinamide (vitamin B3)
omega-3 fatty acids
onion
PABA (para-aminobenzoic acid)
pantothenic acid (vitamin B5)
Pentacyclic triterpenoids
Peptides
Phaeophyceae
phlorotannins
pollen
Polygonum
Premna
proanthocyanidins
protein
quail egg
quercetin
reishi mushroom
rice
rockweed
royal jelly
seaweed
selenium
Selenomethionine
silica
silicon
spinach
spirulina
Terminalia
thyroid substance
trace minerals
vitamin A
vitamin B
vitamin B12
vitamin B6
vitamin C
vitamin D
vitamin D3
vitamin E
Walnut
White Tea
Winter Savory
Withanolides
Zinc
