Evidence supporting the use of: Goldenseal
For the health condition: Halitosis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Goldenseal (Hydrastis canadensis) has a long history of use in traditional herbal medicine, particularly among Native American groups and later by Western herbalists. It has been employed for a variety of ailments, including those related to the mucous membranes and digestive tract. Its use for halitosis (bad breath) is primarily rooted in its reputation as a natural antimicrobial and anti-inflammatory agent, attributed to its primary active compound, berberine. Traditional practitioners have recommended goldenseal as a mouthwash or gargle to help reduce oral bacteria, which can contribute to foul breath. However, there is little to no direct scientific research specifically investigating goldenseal’s efficacy for halitosis. While in vitro studies have shown that goldenseal and its constituents exhibit broad-spectrum antimicrobial activity, especially against certain bacteria and fungi, clinical trials confirming its benefit for oral malodor in humans are lacking. Therefore, the evidence supporting its use for halitosis is weak and based more on historical and anecdotal reports than on rigorous scientific validation. Individuals considering goldenseal for this purpose should also be aware of potential side effects and consult with healthcare professionals, as goldenseal may interact with medications and is not recommended for long-term use or for certain populations (such as pregnant women).

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