Evidence supporting the use of: Prickly Pear Cactus
For the health condition: Hangover

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Prickly Pear Cactus (Opuntia ficus-indica) has been studied for its potential to reduce hangover symptoms. While it is traditionally used in some cultures for various ailments, its use for hangover relief is supported by limited scientific evidence. The most notable study was published in the journal Archives of Internal Medicine in 2004. This randomized, double-blind, placebo-controlled trial investigated the effects of an extract of prickly pear cactus on healthy volunteers who consumed alcohol. The study found that those who took the extract experienced a significant reduction in the severity of hangover symptoms—specifically nausea, dry mouth, and loss of appetite—compared to the placebo group. The authors suggested that the anti-inflammatory properties of prickly pear may help blunt the increase in C-reactive protein (a marker of inflammation) that occurs after alcohol intake. Despite these findings, the evidence base remains limited, with few high-quality studies and insufficient replication. The mechanism is not completely understood but may relate to the fruit's antioxidant and anti-inflammatory compounds. Overall, while there is some scientific support, particularly from the 2004 trial, more research is needed to firmly establish efficacy and determine optimal dosing and preparation. Thus, the use of prickly pear cactus for hangover relief can be considered "scientific" but with modest supporting evidence.

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