Relationship: Hashimoto's Disease and vitamin D

Evidence supporting the use of: Vitamin D
For the health condition: Hashimoto's Disease

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Source of validity: Scientific
Rating (out of 5): 3

Vitamin D is used to support or treat Hashimoto's Disease based on emerging scientific evidence rather than longstanding tradition. Hashimoto’s Disease is an autoimmune thyroid disorder characterized by chronic inflammation and gradual destruction of the thyroid gland, often leading to hypothyroidism. Numerous studies have observed that patients with Hashimoto's frequently exhibit lower serum vitamin D levels compared to healthy controls. Vitamin D plays a crucial role in immune regulation, modulating both innate and adaptive immune responses, and deficiency has been linked to increased risk and severity of autoimmune diseases, including Hashimoto’s Thyroiditis.

Interventional studies have shown mixed but promising results: supplementation with vitamin D in deficient Hashimoto’s patients has, in some trials, reduced thyroid peroxidase antibodies (TPOAb)—a marker of autoimmune activity—and improved thyroid function, though not all studies consistently demonstrate significant clinical improvements. A 2018 meta-analysis concluded that vitamin D supplementation may decrease antibody levels, particularly in those who are deficient, but called for larger, well-designed trials to confirm these effects and to clarify optimal dosing and duration.

In summary, while vitamin D supplementation is not a primary treatment for Hashimoto’s, its use is justified by moderate scientific evidence, particularly in individuals with documented deficiency. It is generally considered as an adjunct therapy aimed at improving immune function and potentially reducing thyroid autoimmunity, rather than reversing the disease. Clinical guidelines increasingly recommend checking vitamin D levels in patients with Hashimoto’s and correcting deficiencies as part of overall management.

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Evidence supporting the use of: Vitamin D
For the health condition: Hashimoto's Disease

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Other ingredients used for Hashimoto's Disease

Health Concerns

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Evidence supporting the use of: Vitamin DFor the health condition: Hashimoto's Disease

Table of Contents

Synopsis

Other ingredients used for Hashimoto's Disease

Other health conditions supported by vitamin D

Products containing vitamin D

Evidence supporting the use of: Vitamin D
For the health condition: Hashimoto's Disease