Evidence supporting the use of: Paeoniflorin
For the health condition: Headache (general)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Paeoniflorin is a major bioactive compound extracted from the root of Paeonia lactiflora, a traditional Chinese medicinal herb. Historically, Paeonia lactiflora and its preparations (such as Shaoyao and its formulas) have been used in Traditional Chinese Medicine (TCM) for the treatment of various pain conditions, including headache. The use of paeoniflorin-containing herbs for headache is primarily rooted in TCM theory, where it is believed to "soothe the liver," "alleviate pain," and "harmonize the blood." Classic texts and clinical practice have documented the application of Paeonia-based prescriptions in managing headache symptoms, particularly those attributed to internal imbalances such as "liver yang rising" or "blood deficiency."

Modern scientific studies on paeoniflorin's direct effects on headache are limited. Some preclinical research suggests that paeoniflorin possesses anti-inflammatory, neuroprotective, and vasodilatory properties, which could theoretically contribute to headache relief, especially in cases involving neurogenic inflammation or vascular factors. However, these findings are mostly from animal studies or in vitro models, and there are few clinical trials specifically evaluating paeoniflorin or Paeonia extracts for headache in humans. Therefore, the evidence base is primarily traditional, with limited scientific validation to date. The overall evidence rating is 2, reflecting traditional use and weak preliminary pharmacological support but a lack of robust clinical trials.

More about Paeoniflorin
More about Headache (general)

Other ingredients used for Headache (general)

alpha-pinene
green chiretta
apple
ashwagandha
waterhyssop
bamboo
basil
betel
black cumin
black tea
Indian frankincense
burdock
cannabis sativa oil
chamomile
cucumber
turmeric
fennel
feverfew
ginger
ginseng
gooseberry
gotu kola
greek mountain tea
onion
green tea
guayusa
jujube
kudzu
lavender
lemon
licorice root
lovage
magnesium
mint
moringa
mustard seed
peppermint oil
phellodendron amurense
purple butterbur root
quail egg
riboflavin (vitamin B2)
rose oil
sage
schizonepeta
scrophularia root
spearmint leaf
triphala
watermelon
white willow
zhejiang fritillary
cardamom
capsicum
Indian bael
alpinia galangal
clerodendrum indicum
ferula assafoetida
hedychium spicatum
anise
punarnava
commiphora
tinospora cordifolia
blackboard tree
caesalpinia crista
fumaria parviflora
rubia cordifolia
peony
lingusticum wallichii
morus
myrrh
root tuber
silk tree
chrysanthemum
amber
flowering quince
fern
ganoderma
sweetgums
morinda
birch
wintergreen
camphor oil
menthol oil
aster root
yerba mate
wood betony
paw paw
indigo leaves
cayenne pepper
soursop
geranium
1,3,7-Trimethylpurine-2,6-dione
Avens
Apple Cider Vinegar
Agastache
Alpha-terpineol
Ambergris
Ardisia
Angelica
Agrimony
Achyranthes
Abrus
Asarum heterotropoides
Albizia
Aconite
Asafoetida
Ajuga
Aerva lanata
Agarwood
American Liverleaf
Anemone
Asam gelugor
Alsonia scholaris
Agrimonia pilosa
Acetylsalicylic acid
Amor seco
Arani
Arisaema
Atractylone
Betony
Black Seed
Blue Flag
Bryonia
Blackthorn
Broussonetia
Blepharis
Balsam
Bayleaf
Butea monosperma
Barleria
Bitter Grass
Bael
Boswellia
Baccharoides anthelmintica
Banyan
Black willow
black salt
Black Nightshade
Bombax
Borassus Palm
Buddha's Hand
Borassus aethiopum
Black root
Bassia scoparia
Black Hellebore
Balloon Flower
Bergenia
Bottle gourd
Borneol
Camellia sinensis
Chinese Silkvine
Cinnamomum
Clary sage
Clerodendrum trichotomum
Coriander
Clerodendrum phlomidis
Cactus
Cinquefoil
Citron
Carry Me Seed
Cymbopogon Martini
Coca
Campylandra fimbriata
Centipeda
Corktree
Chaenomeles lagenaria
Cannabidiol
Calamus
Chinatree
Corydalis
Cynodon dactylon
Costus
Carthamus
Colocynth
cola nut
Celosia
Clerodendrum indicum
DIVI-DIVI
Dragonhead
Dichrostachys glomerata
European Elder
Erythropalum scandens
Erodium cicutarium
Evodia
English Horsemint
Elephant's Head
Embelia
Eugenol
Fang-Feng
Fernbush
Goldthread
Galangal
Lotus
Little ironweed
Mustard
Mallow
Orchid
Potato
Prickly Pear Cactus
Poppy
Rose
Spikenard
Snakeroot (unspecified)
Sandalwood
Sumac
Sweet Orange alcohol
Vervain
Vinegar
Zucchini

Products containing Paeoniflorin

We currently have no products on Vitabase that contain this ingredient.