Relationship: Heart and vitamin K

Evidence supporting the use of: Vitamin K
For the body system: Heart

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin K is scientifically recognized for its essential role in blood clotting, but emerging research also links it to cardiovascular health. Specifically, vitamin K (particularly K2, or menaquinone) is involved in the regulation of calcium in the blood and in tissues. Adequate vitamin K is necessary for the activation of matrix Gla-protein (MGP), a protein that inhibits vascular calcification—a process implicated in the development of atherosclerosis and heart disease. Several observational studies have shown that higher dietary intake of vitamin K2 is associated with reduced risk of coronary heart disease and lower rates of arterial calcification. For example, the Rotterdam Study (2004) found that people with the highest intake of vitamin K2 had a 57% lower risk of dying from heart disease. However, randomized controlled trials are limited, and while some small studies suggest that supplementation can slow the progression of arterial stiffness, definitive evidence for heart disease prevention or treatment is lacking.

In summary, there is scientific rationale and moderate epidemiological evidence that vitamin K, especially K2, supports heart and vascular health, primarily by inhibiting vascular calcification. However, more large-scale clinical trials are needed to confirm these effects and to clarify whether supplementation translates to significant reductions in cardiovascular events.

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Other body systems supported by vitamin K

Arteries
Blood
Capillaries
Circulatory System
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Structural System
Teeth

Products containing vitamin K

Health Concerns

Brands

Evidence supporting the use of: Vitamin K
For the body system: Heart

Table of Contents

Synopsis

Other ingredients that support Heart

Other body systems supported by vitamin K

Products containing vitamin K

Health Concerns

Brands

Evidence supporting the use of: Vitamin KFor the body system: Heart

Table of Contents

Synopsis

Other ingredients that support Heart

Other body systems supported by vitamin K

Products containing vitamin K

Evidence supporting the use of: Vitamin K
For the body system: Heart