Evidence supporting the use of: Digitalis
For the health condition: Heart Fibrillation or Palpitations

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Digitalis, derived from the foxglove plant (Digitalis purpurea), is scientifically validated for use in certain heart rhythm disorders, particularly atrial fibrillation and atrial flutter. Its primary action is to increase the force of cardiac contraction and to slow conduction through the atrioventricular (AV) node, which helps control ventricular rate in atrial fibrillation. The active compounds, mainly digoxin, inhibit the sodium-potassium ATPase pump, leading to increased intracellular calcium in cardiac cells, thus enhancing contractility and providing a vagomimetic effect that slows AV nodal conduction.

The use of digitalis in atrial fibrillation is well-established in modern medicine, especially in patients with concomitant heart failure where rate control is desired. Numerous clinical trials and decades of use have demonstrated its efficacy in reducing symptoms and controlling heart rate. However, it is not effective for converting atrial fibrillation to normal sinus rhythm or for treating ventricular arrhythmias. Instead, its role is in rate control and symptomatic management. Guidelines from major cardiology societies endorse the use of digoxin (a digitalis glycoside) in specific patient populations.

Nevertheless, digitalis use requires careful dosing and monitoring due to its narrow therapeutic index and potential for toxicity, especially in the elderly or those with renal impairment. In summary, digitalis is strongly supported by scientific evidence for the management of heart rate in atrial fibrillation, justifying its continued use in contemporary medical practice.

More about Digitalis
More about Heart Fibrillation or Palpitations

Products containing Digitalis

We currently have no products on Vitabase that contain this ingredient.