Evidence supporting the use of: Fish oil
For the health condition: Heart Fibrillation or Palpitations

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Fish oil, rich in omega-3 fatty acids (primarily EPA and DHA), has been studied for its effects on various cardiac arrhythmias, including atrial fibrillation (AF) and palpitations. The scientific rationale for its use is based on the observation that omega-3s can modulate cardiac cell membrane stability, reduce inflammation, and potentially decrease susceptibility to abnormal heart rhythms. Early observational and some interventional studies suggested that populations with high omega-3 intake had lower rates of sudden cardiac death and arrhythmias, which led to widespread interest in fish oil for heart rhythm support.

However, more recent, well-controlled clinical trials and meta-analyses have produced mixed or largely negative results regarding the efficacy of fish oil in preventing or treating atrial fibrillation and palpitations. For example, several large studies, including the Omega-3 Fatty Acids for Prevention of Postoperative Atrial Fibrillation (OPERA) trial and others, have failed to demonstrate a significant protective effect of omega-3 supplementation against AF recurrence or onset. Some studies even suggest a potential increase in risk with high-dose supplementation in certain populations.

Overall, while the use of fish oil for heart arrhythmias is grounded in scientific investigation, robust evidence supporting its clinical effectiveness for treating or preventing atrial fibrillation or palpitations is lacking. Current guidelines do not recommend fish oil specifically for arrhythmia management, and its use should be individualized based on broader cardiovascular needs.

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