Evidence supporting the use of: Foxglove
For the health condition: Heart Fibrillation or Palpitations

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Foxglove (Digitalis purpurea) has a well-established scientific basis for its use in certain heart conditions, specifically atrial fibrillation and heart failure. The plant contains cardiac glycosides, most notably digoxin and digitoxin, which have potent effects on heart muscle contractility and electrical conduction. These compounds increase the force of heart contractions and help control heart rate by inhibiting the sodium-potassium ATPase pump in cardiac cells, leading to increased intracellular calcium. This mechanism was first systematically studied in the late 18th century by William Withering, who documented the use of foxglove in treating "dropsy" (edema due to heart failure), and subsequently, its use was adopted in mainstream medicine. Modern clinical practice still utilizes digoxin (derived from foxglove) for rate control in atrial fibrillation (especially when other agents are unsuitable) and for symptomatic relief in certain forms of heart failure. However, its use is more targeted now due to a narrow therapeutic window and risk of toxicity. There are numerous clinical trials and decades of pharmacological data validating its efficacy and safety profile when used appropriately. Therefore, the use of foxglove-derived compounds for heart fibrillation and palpitations is strongly supported by scientific evidence, though it must be administered under strict medical supervision.

More about Foxglove
More about Heart Fibrillation or Palpitations

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