Polygonatum, also known as Solomon’s Seal, has been used in traditional Chinese medicine (TCM) and other herbal systems for centuries. In TCM, Polygonatum species (notably Polygonatum sibiricum, P. odoratum, and P. multiflorum) are believed to "nourish Yin" and "tonify Qi," properties associated with supporting general vitality and, indirectly, heart function, especially in cases described as "heart weakness" or deficiency syndromes. The herb is thought to replenish bodily fluids and support organ systems, including the heart, especially in the context of fatigue, palpitations, and weakness after illness or in the elderly.

However, direct scientific evidence for Polygonatum's effectiveness in treating or supporting heart weakness is limited. While some laboratory and animal studies suggest possible antioxidant, anti-inflammatory, and cardioprotective effects, these findings are preliminary and not specific to clinical heart failure or cardiac weakness in humans. No high-quality clinical trials have demonstrated clear benefits for heart conditions. Thus, the use of Polygonatum for heart weakness is primarily justified by its long history in traditional medicine rather than by robust scientific evidence.

In summary, while Polygonatum is traditionally used to support the heart and general vitality, current evidence supporting its use for heart weakness is rooted in historical practice rather than modern clinical research.