Evidence supporting the use of: Vitamin B1 (thiamin pyrophosphate)
For the health condition: Heart (weakness)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin B1 (thiamin pyrophosphate) has scientific support for its use in treating certain types of heart weakness, primarily in the context of thiamine deficiency. Thiamine deficiency can lead to a condition known as "wet beriberi," which is characterized by heart failure, peripheral edema, and other cardiovascular symptoms. This condition was historically prevalent in populations relying heavily on polished rice, which lacks thiamine. Administration of thiamine can rapidly reverse the cardiac manifestations of beriberi, providing clear evidence that thiamine is essential for normal heart function.

Beyond deficiency states, some studies have examined the use of thiamine supplementation in patients with chronic heart failure, even when overt deficiency is not present. Small clinical trials and observational studies have reported that thiamine supplementation may improve left ventricular ejection fraction and symptoms in patients with heart failure, particularly those on long-term diuretic therapy, which can increase urinary thiamine loss. However, these studies are limited in size and quality, and larger, well-controlled trials are needed for definitive conclusions.

In summary, the use of thiamine (vitamin B1) to treat heart weakness is strongly supported in cases of deficiency, with rapid and dramatic benefits. There is some, but less robust, evidence for benefit in chronic heart failure not directly linked to deficiency. Thus, the scientific evidence is moderate, especially strong in deficiency-related cardiac conditions.

More about Vitamin B1 (thiamin pyrophosphate)
More about Heart (weakness)

Other health conditions supported by Vitamin B1 (thiamin pyrophosphate)

Alcoholism
Congestive Heart Failure
Diabetes
Fatigue
Heart (weakness)
Peripheral Neuropathy

Products containing Vitamin B1 (thiamin pyrophosphate)

We currently have no products on Vitabase that contain this ingredient.