Evidence supporting the use of: Vitamin E (not specified)
For the health condition: Heart (weakness)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 1

Vitamin E has been studied for its potential role in cardiovascular health, particularly due to its antioxidant properties, which were hypothesized to help prevent the oxidation of low-density lipoprotein (LDL) cholesterol—a key step in the development of atherosclerosis. Early observational studies suggested that higher intake of vitamin E from diet or supplements might be associated with a lower risk of coronary heart disease. However, large randomized controlled trials and meta-analyses in the past two decades have largely failed to show a benefit of vitamin E supplementation in preventing or treating heart disease or "heart weakness" (a nonspecific term that might refer to heart failure or general cardiovascular dysfunction). Some studies have even indicated potential harm with high-dose supplementation, such as an increased risk of heart failure or hemorrhagic stroke. As a result, major health organizations, including the American Heart Association, do not recommend vitamin E supplements for cardiovascular disease prevention or treatment. Thus, while there is a scientific rationale based on antioxidant theory, the clinical evidence does not support the use of vitamin E for strengthening the heart or treating cardiovascular weakness.

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