Evidence supporting the use of: Alpha lipoic acid
For the health condition: Heavy Metal Poisoning
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Alpha lipoic acid (ALA) is a naturally occurring antioxidant that has garnered attention for its potential use in treating heavy metal poisoning. The rationale behind its use is primarily scientific, rooted in its ability to chelate (bind to) metal ions and facilitate their excretion from the body. Animal studies and some in vitro experiments have shown that ALA can bind to toxic metals such as mercury, arsenic, and cadmium, potentially reducing their toxicity and promoting their removal. Additionally, ALA has been observed to regenerate other antioxidants such as glutathione, which plays a critical role in detoxifying heavy metals.
However, the clinical evidence supporting ALA’s effectiveness in treating heavy metal poisoning in humans is limited. Most of the available data come from preclinical studies, with few well-designed human trials. Some case reports and small clinical studies suggest modest benefits, but these are not sufficient to establish ALA as a standard treatment. The primary chelating agents used in clinical practice remain substances like dimercaprol, EDTA, and DMSA, which have more robust evidence and regulatory approval.
In summary, while there is a scientific basis for ALA’s potential as a supportive agent in heavy metal detoxification, the evidence is not strong enough to recommend it as a first-line therapy. More rigorous human studies are needed to clarify its efficacy and safety profile in this context.
More about alpha lipoic acid
More about Heavy Metal Poisoning
Other health conditions supported by alpha lipoic acid
Aging (prevention)Alzheimer's Disease
Arteriosclerosis
Arthritis
Athletic and Exercise Aids
Autoimmune Disorders
Body Building
Burning Feet or Hands
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Carpal Tunnel Syndrome
Cataracts
Chemical Poisoning
Chemotherapy (reducing side effects)
Circulation (poor)
Circulation (to the brain)
Cirrhosis of the Liver
Diabetes
Diabetic Retinopathy
Fatigue
Fatty Liver Disease
Free Radical Damage
Glaucoma
Heavy Metal Poisoning
Hypertension
Inflammation
Liver Detoxification
Memory and Brain Function
Metabolic Syndrome
Migraine
Multiple Sclerosis
Nerve Damage
Neuralgia and Neuritis
Numbness
Parkinson's Disease
Peripheral Neuropathy
Rheumatoid Arthritis
Strokes
Triglycerides (high)
Wounds and Sores
Products containing alpha lipoic acid
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Klean Athlete
Klean Antioxidant ™
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