Evidence supporting the use of: Humic acid
For the health condition: Heavy Metal Poisoning

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Humic acid is used in some alternative and integrative medicine practices for heavy metal poisoning, and there is a limited but growing body of scientific evidence supporting its potential chelating properties. Humic substances, including humic acid, are large, naturally occurring organic molecules found in soil, peat, and water. They have a high affinity for binding metal ions due to their numerous functional groups, such as carboxyl and phenolic hydroxyls. Preclinical studies (primarily in vitro and in animal models) have demonstrated that humic acid can bind heavy metals like lead, cadmium, and mercury, potentially reducing their bioavailability and toxicity. For example, studies have shown that humic acid can decrease the absorption and tissue accumulation of these metals in animals, and may increase their excretion. However, robust clinical trials in humans are lacking. Most available data come from laboratory or animal research, and there are significant differences between experimental settings and human physiology. While some traditional medicine systems have used humic substances for detoxification, these uses are not well-documented or specific to heavy metal poisoning. Overall, the scientific evidence supporting humic acid for heavy metal poisoning is preliminary, and its safety and efficacy in humans remain to be established through well-designed clinical research.

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