Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Zeolites are microporous, aluminosilicate minerals commonly used in industrial and environmental applications for their capacity to adsorb heavy metals and other toxins. Their use in human health, particularly for heavy metal detoxification, has gained popularity in recent years. The proposed mechanism relies on zeolite's ability to bind heavy metals such as lead, mercury, cadmium, and arsenic in the gastrointestinal tract, thus reducing absorption and promoting excretion. Several in vitro and animal studies have shown that certain forms of zeolite, such as clinoptilolite, can adsorb heavy metals and reduce their bioavailability. For example, animal models demonstrate reduced tissue accumulation of lead and cadmium after zeolite administration.

However, clinical evidence in humans is limited and of variable quality. Some small-scale human trials and case reports suggest potential benefit, but these studies often lack rigorous controls, have small sample sizes, or use surrogate biomarkers rather than direct clinical endpoints. The safety profile of zeolite seems favorable when purified and used appropriately, but questions remain about its efficacy, optimal dosing, and long-term effects. Regulatory agencies have not endorsed zeolite as a treatment for heavy metal poisoning, and it is not recognized as a standard therapy. In summary, while there is some scientific rationale and preclinical evidence for zeolite use in heavy metal detoxification, robust clinical data is lacking, justifying a moderate-low evidence score.

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