Evidence supporting the use of: Bioflavonoids
For the health condition: Hemorrhoids

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bioflavonoids, particularly the subgroup known as “diosmin” and “hesperidin” (often derived from citrus fruits), have been studied for their effects on hemorrhoidal disease. Scientific evidence primarily comes from randomized clinical trials and meta-analyses, which indicate that certain bioflavonoid preparations can reduce the severity and duration of symptoms such as bleeding, pain, and swelling in acute hemorrhoidal episodes. The mechanism is thought to involve strengthening capillary walls, reducing vascular permeability, and exerting anti-inflammatory effects. A 2012 Cochrane review and other systematic reviews have concluded that flavonoid mixtures (often termed “micronized purified flavonoid fraction,” containing both diosmin and hesperidin) are more effective than placebo in improving symptoms of hemorrhoids and reducing the risk of recurrence. However, the overall quality of the evidence is moderate, with some studies exhibiting methodological limitations, such as small sample sizes and heterogeneity in outcome measures. Most research focuses on specific bioflavonoid combinations rather than “bioflavonoids (unspecified),” so generalization to all bioflavonoids is limited. In summary, while there is scientific evidence—particularly for certain flavonoid preparations—supporting the use of bioflavonoids in the treatment of hemorrhoids, this evidence is not robust for all forms of bioflavonoids, and optimal dosing and formulations remain to be standardized.

More about bioflavonoids
More about Hemorrhoids

Other ingredients used for Hemorrhoids

Abrus
Acacia
Achyranthes
Aconite
Aerva lanata
Aescin
Agrimonia pilosa
Agrimony
Ajuga
Alchemilla
Allicin
Allium tuberosum
Aloe vera
American Liverleaf
Amor seco
Angelica
anthocyanidins
anthraquinone
Antirrhinum majus
antler
apple
apple cider vinegar
apricot
Ardisia
aster root
avens
bael
Baliospermum
banyan
Barleria
Bassia scoparia
bayleaf
Bergenia
betel
bilberry
bioflavonoids
birch
Black Hellebore
black nightshade
black root
blackberry
blackboard tree
Blepharis
Borassus aethiopum
borassus palm
bran
Brassica
butcher's broom
cabbage
cactus
Caesalpinia crista
capsicum
Carthamus
castor oil
Celosia
chamomile
chard
chestnut
Chinese silkvine
Chondrus
cinquefoil
citrus bioflavonoids
Clerodendrum indicum
coconut oil
colocynth
commiphora
Cucurbita
Cyathula
Cynodon dactylon
dandelion
Dianthus
Diosmin
elephant\'s head
Embelia
escin
fiber
fiber blend (proprietary)
Ficus simplicissima
geranium
gotu kola
green chiretta
hazelnut
horse chestnut
Indian coraltree
Kokilaksha
labrador tea
lemon
lichen
licorice root
little ironweed
Lycopodium
Methylcellulose
Mezoneuron benthamianum
Morinda
Morning glory
Morus
Mountain Pepper
Mucilage
Myrrh
Nettle
Nimbidin
Nymphaea nouchali
Oak
Oligomeric proanthocyanidins
Onosma bracteatum
oregon grape
Oroxylum indicum
pagoda tree
Papayotin
parsley
paw paw
Pentacyclic triterpenoids
peony
Persimmon
phellodendron amurense
Pluchea
plum fruit
Polygonum
Portulaca
proanthocyanidins
prune
Prunus
psyllium
punarnava
rhubarb
Rosa laevigata
Rosabin
Rubia cordifolia
Ruscogenins
Ruscus
rutin
Rutosides
Sanguisorba
Sarivan
sea salt
seaweed
Shark Liver Oil
shepherd's purse
slippery elm bark
Sumac
Sword Bean
Szechuan lovage
Tamarind
Tannins
Taraxacin
Terminalia
Triphala
Troxerutin
turmeric
Varuna
vitamin C
Wax Gourd
Winter Begonia
Witch Hazel
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Zinc
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Products containing bioflavonoids

We currently have no products on Vitabase that contain this ingredient.