Evidence supporting the use of: Bioflavonoids (mixture)
For the health condition: Hemorrhoids

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Bioflavonoids, particularly the mixture known as citrus bioflavonoids (often including hesperidin, diosmin, and rutin), have a long history of traditional use in the management of hemorrhoids. The rationale behind their use stems from their purported ability to strengthen capillaries, reduce vascular permeability, and exert anti-inflammatory effects. In Europe, micronized purified flavonoid fractions (MPFF)—primarily diosmin combined with hesperidin—are widely used for chronic venous insufficiency and hemorrhoidal disease, reflecting their acceptance in traditional and clinical practice. Scientific literature provides some support for their benefit, but the quality and conclusiveness of evidence vary. A few randomized controlled trials and meta-analyses suggest that flavonoid mixtures may reduce symptoms such as bleeding, pain, and recurrence rates compared to placebo, especially in acute hemorrhoidal episodes. However, most studies are modest in size, with variable quality and methodology, and often focus on specific semi-synthetic flavonoids (like MPFF) rather than generic "bioflavonoid mixtures". The mechanism is believed to involve venotonic and anti-inflammatory properties. Overall, while there is a historical and traditional basis for the use of bioflavonoids (mixtures) in hemorrhoid management, and some supportive clinical data—mainly for specific preparations—the evidence is not robust or universally accepted. Therefore, their use is best described as traditional with moderate but not strong scientific support.

More about Bioflavonoids (mixture)
More about Hemorrhoids

Other ingredients used for Hemorrhoids

Aloe vera
green chiretta
apple
apricot
berry flavor
betel
bilberry
blackberry
butcher's broom
chamomile
citrus bioflavonoids
turmeric
dandelion
fiber blend (proprietary)
gotu kola
cellulose
horse chestnut
lemon
licorice root
Nettle
oregon grape
parsley
phellodendron amurense
plum fruit
prune
psyllium
rutin
slippery elm bark
Triphala
vitamin C
seaweed
Zinc
capsicum
punarnava
commiphora
blackboard tree
Caesalpinia crista
Rubia cordifolia
peony
Szechuan lovage
Morus
Myrrh
Morinda
birch
aster root
shepherd's purse
paw paw
geranium
sea salt
avens
apple cider vinegar
antler
anthraquinone
Ardisia
Angelica
Acacia
Agrimony
Allicin
Antirrhinum majus
Achyranthes
Abrus
Alchemilla
Aconite
Ajuga
Aerva lanata
American Liverleaf
Aescin
anthocyanidins
Agrimonia pilosa
Allium tuberosum
Amor seco
Baliospermum
Blepharis
Brassica
bayleaf
bran
Barleria
bael
banyan
bioflavonoids
black nightshade
borassus palm
Borassus aethiopum
black root
Bassia scoparia
Black Hellebore
Bergenia
Chinese silkvine
Cucurbita
coconut oil
cactus
cinquefoil
Cyathula
chard
cabbage
chestnut
Cynodon dactylon
castor oil
Carthamus
colocynth
Celosia
Clerodendrum indicum
Chondrus
Dianthus
Diosmin
elephant\'s head
escin
Embelia
fiber
Ficus simplicissima
hazelnut
Indian coraltree
Kokilaksha
lichen
Lycopodium
labrador tea
little ironweed
Methylcellulose
Mezoneuron benthamianum
Mountain Pepper
Mucilage
Morning glory
Nymphaea nouchali
Nimbidin
Oak
Oroxylum indicum
Oligomeric proanthocyanidins
Onosma bracteatum
pagoda tree
Pluchea
Prunus
Pentacyclic triterpenoids
proanthocyanidins
Portulaca
Persimmon
Papayotin
Polygonum
Rosabin
Ruscus
Ruscogenins
Rosa laevigata
Rutosides
rhubarb
Shark Liver Oil
Sanguisorba
Sarivan
Sumac
Sword Bean
Terminalia
Tannins
Taraxacin
Troxerutin
Tamarind
Varuna
Wax Gourd
Witch Hazel
Winter Begonia
Yellow Dock
Zucchini

Products containing Bioflavonoids (mixture)

We currently have no products on Vitabase that contain this ingredient.